The Canes I cluster of 24 major galaxies and dozens of smaller satellite galaxies has been a target of exploration and colonization after Year 5000 by both the Star Imperium and the later United Planets.  It is millions of light years from the Local Group.  The number of Jumpgates has slowly but steadily increased over the millennnia.

Until Year 8180, all of the Canes I Group and the M81 Group constituted the same Stellar sector, but since then the M81 Group has been divided into a number of sectors each containing multiple galaxies. Since Year 8919, the sectors in this part of the universe have been divided into Subsectors. The two sector of the Canes I Group are Intergalactic sectors:

the NGC 4449 Sector, closest to the Local Group

The M94 Sector, further from the Local Group.

Population breakdown for all sectors and subsectors in Canes I Group:  Native races 85%, Orks 8%, Humans 5%, Asguardian Dwarfs 1%, other races from Local Group, 1%